Home » News » Structural basis for nucleolin recognition of MYC promoter G-quadruplex | Science

Structural basis for nucleolin recognition of MYC promoter G-quadruplex | Science

Structural basis for nucleolin recognition of MYC promoter G-quadruplex | Science
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The MYC oncogene promoter G-quadruplex (MycG4) regulates transcription and is a prevalent G4 locus in immortal cells. Nucleolin, a major MycG4-binding protein, exhibits greater affinity for MycG4 than for nucleolin recognition element (NRE) RNA. …

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